Assessment and Maintenance of Unigametic Germline Inheritance for C. elegans (Developmental Cell)

Non-Mendelian inheritance in C. elegans results in chimeric animals with cells containing only maternal or paternal nuclear DNA. Artiles et al. develop a toolkit of strains with a high frequency of non-Mendelian segregation and monitor inheritance by fluorescence, thereby enabling experiments requiring detection of non-canonical inheritance events across large populations.