Assessing the Role and Optimal Duration of Hormonal Treatment in Association with Salvage Radiation Therapy After Radical Prostatectomy: Results from a Multi-Institutional Study (European Urology)

The oncological benefit of hormonal therapy (HT) duration among men receiving salvage radiation therapy for increasing prostate-specific antigen after radical prostatectomy depends on their clinical and pathological characteristics. Our data suggest a significant effect of long-term HT for patients with two or more adverse features. Conversely, short-term HT was sufficient for patients with a single risk factor, whereas patients without any risk factors did not show a significant benefit from concomitant HT.