Spatial and Spectral Mapping and Decomposition of Neural Dynamics and Organization of the Mouse Brain with Multispectral Optoacoustic Tomography (Cell Reports)

Olefir et al. apply multispectral optoacoustic (photoacoustic) tomography (MSOT) for noninvasive spatial and spectral mapping and decomposition of neural dynamics and organization of the intact mouse brain in vivo. The results extend the boundaries of noninvasive high-resolution observations beyond the reach of intravital optical neuroimaging in small-animal studies.