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RSS FeedsCytomegalovirus Infection Drives Avidity Selection of Natural Killer Cells (Immunity)

 
 

16 may 2019 04:01:17

 
Cytomegalovirus Infection Drives Avidity Selection of Natural Killer Cells (Immunity)
 




NK cells are innate lymphocytes capable of `adaptive` responses after infection, but whether they undergo avidity selection is unknown. Adams et al. report that diversity in antigen receptor Ly49H expression drives NK cell functional heterogeneity during MCMV infection with high-avidity NK cells being selected to dominate the adaptive response.


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39 viewsCategory: Immunology
 
Distinct Surface Expression of Activating Receptor Ly49H Drives Differential Expansion of NK Cell Clones upon Murine Cytomegalovirus Infection (Immunity)
Stromal IL-33 balances fat stores (Nature Reviews Immunology)
 
 
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