Comparative experimental studies of fuel sprays evolution dynamics in a constant volume chamber were carried out with a view to reduce the uneven distribution of diesel fuel in the combustion chamber when the Common Rail injector is inclined. The fuel sprays was captured by a high-speed camera with simultaneous recording of control pulses of camera and injector on an oscilloscope. Two eight-hole diesel injectors were investigated: One injector with identical orifice diameter (nozzle 1) and another injector with four orifices of the same diameter as orifices of nozzle 1 and four orifices of enlarged diameters (nozzle 2). Both injectors were tested at rail pressure from 100 to 165 MPa and injector control pulse width of 1.5 ms. The dynamics of changes in the spray penetration length and spray cone angle were determined. It was found that sprays develop differently in nozzle 1 fuel. The difference in the length of fuel sprays is 10–15 mm. As for nozzle 2, the fuel sprays develop more evenly: The difference in length is no more than 3–5 mm. The difference of the measured fuel spray cone angles for nozzle 1 is 0.5°–1.5°, and for nozzle 2 is 3.0°–4.0°. It is concluded that the differential increase in the diameters of nozzle orifices, the axes of which are maximally deviated from the injector axis, makes it possible to reduce the uneven distribution of fuel in the combustion chamber and improve the combustion process and the diesel performance as a whole.