The Prevotella copri Complex Comprises Four Distinct Clades Underrepresented in Westernized Populations (Cell Host & Microbe)

Tett et al. find that the intestinal microbe Prevotella copri encompasses four distinct clades constituting the P. copri complex. The complex is prevalent in non-Westernized populations where co-presence of all clades is commonly observed within individuals. Analysis of ancient stool samples supports Westernization as contributing to reduced P. copri prevalence.