Cell Biology
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11 december 2019 04:00:09 |
| A TAZ-AXL-ABL2 Feed-Forward Signaling Axis Promotes Lung Adenocarcinoma Brain Metastasis (Cell Reports) |
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Tweet Brain metastases are a devastating complication of lung cancer with limited therapeutic options. Here Hoj et al. identify a TAZ-AXL-ABL2 autocrine signaling axis required for lung adenocarcinoma brain metastasis that is amenable to pharmacologic inhibition by BBB-penetrant ABL kinase inhibitors. |
| 180 viewsCategory: Cell Biology |
 CD36-Mediated Metabolic Rewiring of Breast Cancer Cells Promotes Resistance to HER2-Targeted Therapies (Cell Reports)A Tumor-Specific Super-Enhancer Drives Immune Evasion by Guiding Synchronous Expression of PD-L1 and PD-L2 (Cell Reports) 
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