Cell Biology
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31 august 2017 17:36:39 |
| Single-Molecule Imaging Reveals How Mre11-Rad50-Nbs1 Initiates DNA Break Repair (Molecular Cell) |
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Tweet Myler et al. directly observe how Mre11-Rad50-Nbs1 (MRN) recognizes DNA breaks, removes Ku, and promotes DNA resection to initiate homologous recombination. Overall, their results provide a mechanism for double-strand break repair initiation at protein-occluded DNA ends. |
| 185 viewsCategory: Molecular Biology, Cell Biology |
 The DNA Damage Checkpoint Eliminates Mouse Oocytes with Chromosome Synapsis Failure (Molecular Cell)The RNA m6A Reader YTHDF2 Is Essential for the Post-transcriptional Regulation of the Maternal Transcriptome and Oocyte Competence (Molecular Cell) 
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