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9 november 2017 17:33:52

 
Higher-Order Kidney Organogenesis from Pluripotent Stem Cells (Cell Stem Cell)
 




Taguchi and Nishinakamura define signals that specifically induce ureteric bud and nephron progenitor lineages from PSCs. Co-culturing these progenitors can generate organoids that mimic organotypic architecture of the embryonic kidney with nephrons interconnected by branched epithelium, showing that higher-order organogenesis can be recapitulated in PSC-derived organoids.


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291 viewsCategory: Cell Biology
 
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