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RSS FeedsMis16 Switches Function from a Histone H4 Chaperone to a CENP-ACnp1-Specific Assembly Factor through Eic1 Interaction (Structure)

 
 

25 may 2018 06:01:26

 
Mis16 Switches Function from a Histone H4 Chaperone to a CENP-ACnp1-Specific Assembly Factor through Eic1 Interaction (Structure)
 


Using structural, biochemical, and genetic approaches, An et al. unravel the oligomeric state of the fission yeast Mis18 holo-complex and the molecular mechanism by which Mis16 performs its centromere-specific function upon binding to Eic1.


 
87 viewsCategory: Biochemistry
 
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