Protein Acylation is a General Regulatory Mechanism in Biosynthetic Pathway of Acyl-CoA-Derived Natural Products (Cell Chemical Biology)

Xu et al. systematically investigated the general interplay between beneficial and adverse effects of cellular acyl-CoA concentrations on the biosynthesis of acyl-CoA-derived natural products in bacteria, which provided insight into the potential function of the identified lysine acylation substrates.