Enhancing Oligodendrocyte Myelination Rescues Synaptic Loss and Improves Functional Recovery after Chronic Hypoxia (Neuron)

Wang et al. demonstrate that hypomyelination specifically contributes to the significant loss of excitatory synapses and prolonged functional deficits after chronic hypoxia and that myelination-enhancing strategies represent a promising approach for functional recovery following hypoxic WMI.