Biochemistry
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17 august 2018 06:00:08 |
| Inhibition of K-RAS4B by a Unique Mechanism of Action: Stabilizing Membrane-Dependent Occlusion of the Effector-Binding Site (Cell Chemical Biology) |
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Tweet Fang et al. have elucidated a membrane-dependent mechanism by which a small-molecule inhibitor of KRAS binds at the protein-membrane interface and stabilizes KRAS in an orientation in which its effector-binding site is occluded by the membrane. |
| 57 viewsCategory: Biology, Chemistry, Biochemistry |
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