Rapid Disruption of Dishevelled Activity Uncovers an Intercellular Role in Maintenance of Prickle in Core Planar Polarity Protein Complexes (Cell Reports)

Ressurreição et al. have developed tools to rapidly disrupt protein function in Drosophila and used these to investigate the function of the protein Dishevelled in planar polarity. They find a continuous requirement for Dishevelled in core planar polarity complex maintenance with its loss causing relocalization of Prickle in neighboring cells.