Re: John L. Gore, Jonathan L. Wright. Can We Prevent Bladder Cancer Recurrences? Eur Urol. In press. https://doi.org/10.1016/j.eururo.2018.10.008 (European Urology)

In their interesting editorial [1] discussing the recently published BOXIT trial [2], Gore and Wright commented on ways urologists can prevent non-muscle-invasive bladder cancer (NMIBC) recurrences. These included a diet abundant in fruits and vegetables, maintaining an ideal weight, and smoking cessation. Importantly, one factor not mentioned was the avoidance of a high intake of synthetic folic acid, since it has been shown that excessive folic acid (but not natural folate) promotes the recurrence of NMIBC in patients [3].