Molecular Basis of Mannose Recognition by Pradimicins and their Application to Microbial Cell Surface Imaging (Cell Chemical Biology)

Nakagawa et al. report the structural elucidation of pradimicin (PRM) dimer, and provide a possible answer as to how PRM recognizes mannose (Man). They also disclose that an azide-functionalized PRM retains mannose binding specificity in water, and fluorescently stains cell wall mannans of Candida rugosa.