Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity (Cell Metabolism)

Bravo-San Pedro et al. investigate the physiological role of the autophagic regulator ACBP, describing that the protein is increased in obese individuals and favors lipogenesis in mouse models, whereas its neutralization reduces the propensity of mice to gain weight in the context of a high-fat diet.