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RSS FeedsWithdrawal: Protein kinase C{zeta}-dependent LKB1 serine 428 phosphorylation increases LKB1 nucleus export and apoptosis in endothelial cells. [Withdrawals/Retractions] (Journal of Biological Chemistry)

 
 

13 september 2019 10:01:28

 
Withdrawal: Protein kinase C{zeta}-dependent LKB1 serine 428 phosphorylation increases LKB1 nucleus export and apoptosis in endothelial cells. [Withdrawals/Retractions] (Journal of Biological Chemistry)
 


VOLUME 283 (2008) PAGES 12446-12455This article has been withdrawn by the authors. The Journal raised questions that the Akt immunoblot in Fig. 2B was reused in Fig. 6E, lanes 2 and 5 of the Akt immunoblot in Fig. 2C were duplicated, lanes 4 and 5 of the Akt immunoblot in Fig. 2C were reused in lanes 5 and 6 of the Akt immunoblot in Fig. 5C, lanes 2 and 5 of the Akt immunoblot were duplicated in Fig. 5C, the first lane of the PKC? immunoblot in Fig. 4B was reused in Fig. 7A as Akt, and lanes 1 and 6 of the Akt immunoblot in Fig. 4C were duplicated. The authors were able to locate some of the original data and repeated experiments performed at the time of the original work, which the authors state support the conclusions of the paper. The authors state that the results of this paper are confirmed by the results of complementary experiments presented in the article, and some of the principal observations of this paper were further confirmed in publications from other laboratories (Elshaer, S. L. et al. (2018) Antioxidants 7, 47; Heo, K. S. et al. (2011) J. Cell Biol. 193, 867-884; Tommasini, I. et al. (2008) J. Immunol. 181, 5637-5645). The authors stand by the conclusions of the paper.


 
210 viewsCategory: Biochemistry
 
Withdrawal: Thromboxane A2 receptor activates a Rho-associated kinase/LKB1/PTEN pathway to attenuate endothelium insulin signaling. [Withdrawals/Retractions] (Journal of Biological Chemistry)
Withdrawal: A novel germ line-specific gene of the phosducin-like protein (PhLP) family: A meiotic function conserved from yeast to mice. [Withdrawals/Retractions] (Journal of Biological Chemistry)
 
 
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