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18 june 2018 14:00:19

 
Kinetics and Fidelity of the Repair of Cas9-Induced Double-Strand DNA Breaks (Molecular Cell)
 




Brinkman etáal. report a strategy to determine the rate and fidelity of double-strand break repair at single loci cut by Cas9. They also infer the contributions from different repair pathways. Cas9-induced breaks are repaired at variable but often slow rates, and the repair tends to be error prone.


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