Oncology
 |
|
30 november 2018 23:00:03 |
| Enhancer Architecture and Essential Core Regulatory Circuitry of Chronic Lymphocytic Leukemia (Cancer Cell) |
|
Tweet Analyzing integrative enhancer profiles and transcription factor dependencies, Ott et al. construct enhancer-based core regulatory circuits of chronic lymphocytic leukemia (CLL) and reveal a dominant and essential role for PAX5. BET inhibition disrupts CLL super enhancer networks and suppresses CLL growth. |
| 205 viewsCategory: Cell Biology, Oncology |
 KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance (Cancer Cell)A Transcription Factor Addiction in Leukemia Imposed by the MLL Promoter Sequence (Cancer Cell) 
|
| blog comments powered by Disqus |
MyJournals.org
The latest issues of all your favorite science journals on one page
The latest issues of all your favorite science journals on one page
