Cell Biology
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13 november 2019 03:04:30 |
| CCDC84 Acetylation Oscillation Regulates Centrosome Duplication by Modulating HsSAS-6 Degradation (Cell Reports) |
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Tweet Wang et al. show that CCDC84 prevents centrosome overduplication by facilitating APC/CCdh1-mediated HsSAS-6 degradation at mitotic exit. SIRT1 and NAT10 regulate the acetylation of CCDC84 at lysine 31, and only acetylated CCDC84 promotes HsSAS-6 binding to APC/CCdh1. |
| 195 viewsCategory: Cell Biology |
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