Recent XAS studies into Homogeneous metal catalyst in fine chemical and pharmaceutical syntheses (Epidemiologic Perspectives & Innovations)

A brief review of studies using X-ray Absorption Spectroscopy (XAS) to investigate homogeneous catalytic reactions in fine chemical and pharmaceutical context since 2010 is presented. The advantages of the techniques over traditional lab-based analytical tools, particularly when NMR spectroscopy fails to deliver mechanistic insights, are summarised using these examples. A discussion on the current limitations of the techniques and challenges in the near future is also included.Graphical abstractA minireview of recent developments in application of X-ray Absorption Spectroscopy as an effective mechanistic tool to synthetic catalytic reactions relevant to fine chemical and pharmaceutical syntheses.