Immunology
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17 september 2019 22:03:50 |
| Why Is IFN-? Less Inflammatory? One IRF Decides (Immunity) |
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Tweet Type I and type III interferons (IFNs) activate similar antiviral transcriptional programs, but the type I IFN response is more inflammatory. In this issue of Immunity, Forero et al. find that selective induction of the transcription factor IRF1 promotes proinflammatory chemokine expression downstream of type I IFN signaling. |
| 237 viewsCategory: Immunology |
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