Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses (Cell Reports)

TP53 is one of the most frequently mutated genes in cancer; however, its significance in controlling tumor-immune crosstalk is not fully understood. Blagih et al. highlight a key role for tumor-associated loss of p53, a common oncogenic event, in regulating myeloid and T cell responses.