MyJournals Home  

RSS FeedsIJMS, Vol. 21, Pages 684: Natural Polyphenols Targeting Senescence: A Novel Prevention and Therapy Strategy for Cancer (International Journal of Molecular Sciences)

 
 

21 january 2020 01:03:04

 
IJMS, Vol. 21, Pages 684: Natural Polyphenols Targeting Senescence: A Novel Prevention and Therapy Strategy for Cancer (International Journal of Molecular Sciences)
 


Cancer is one of the most serious diseases endangering human health. In view of the side effects caused by chemotherapy and radiotherapy, it is necessary to develop low-toxic anti-cancer compounds. Polyphenols are natural compounds with anti-cancer properties and their application is a considerable choice. Pro-senescence therapy is a recently proposed anti-cancer strategy and has been shown to effectively inhibit cancer. It is of great significance to clarify the mechanisms of polyphenols on tumor suppression by inducing senescence. In this review, we delineated the characteristics of senescent cells, and summarized the mechanisms of polyphenols targeting tumor microenvironment and inducing cancer cell senescence for cancer prevention and therapy. Although many studies have shown that polyphenols effectively inhibit cancer by targeting senescence, it warrants further investigation in preclinical and clinical studies.


 
63 viewsCategory: Biochemistry, Biophysics, Molecular Biology
 
IJMS, Vol. 21, Pages 685: Dissecting Molecular Features of Gliomas: Genetic Loci and Validated Biomarkers (International Journal of Molecular Sciences)
IJMS, Vol. 21, Pages 683: Topical Therapy with Antisense Tumor Necrosis Factor Alpha Using Novel ?-Glucan-Based Drug Delivery System Ameliorates Intestinal Inflammation (International Journal of Molecular Sciences)
 
 
blog comments powered by Disqus


MyJournals.org
The latest issues of all your favorite science journals on one page

Username:
Password:

Register | Retrieve

Search:

Molecular Biology


Copyright © 2008 - 2020 Indigonet Services B.V.. Contact: Tim Hulsen. Read here our privacy notice.
Other websites of Indigonet Services B.V.: Nieuws Vacatures News Tweets Nachrichten