Immunology
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18 february 2020 21:00:06 |
| Febrile Temperature Critically Controls the Differentiation and Pathogenicity of T Helper 17 Cells (Immunity) |
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Tweet Fever has been proposed to have an evolutionarily conserved protective role in infectious diseases. In this study, Wang et al. demonstrate a selective role of fever in boosting Th17 cell differentiation and associated pathogenic functions in autoimmune diseases via heat-shock-response-induced SMAD4 SUMOylation. |
| 183 viewsCategory: Immunology |
 Quorum Regulation via Nested Antagonistic Feedback Circuits Mediated by the Receptors CD28 and CTLA-4 Confers Robustness to T Cell Population Dynamics (Immunity)Interleukin-17A Serves a Priming Role in Autoimmunity by Recruiting IL-1?-Producing Myeloid Cells that Promote Pathogenic T Cells (Immunity) 
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