This paper elucidates the development of a deep learning–based driver assistant that can prevent driving accidents arising from drowsiness. As a precursor to this assistant, the relationship between the sensation of sleep depravity among drivers during long journeys and CO2 concentrations in vehicles is established. Multimodal signals are collected by the assistant using five sensors that measure the levels of CO, CO2, and particulate matter (PM), as well as the temperature and humidity. These signals are then transmitted to a server via the Internet of Things, and a deep neural network utilizes this information to analyze the air quality in the vehicle. The deep network employs long short-term memory (LSTM), skip-generative adversarial network (GAN), and variational auto-encoder (VAE) models to build an air quality anomaly detection model. The deep learning models gather data via LSTM, while the semi-supervised deep learning models collect data via GANs and VAEs. The purpose of this assistant is to provide vehicle air quality information, such as PM alerts and sleep-deprived driving alerts, to drivers in real time and thereby prevent accidents.