Copper-catalyzed O-alkenylation of phosphonates (Beilstein Journal of Organic Chemistry)

Abstract Copper catalysis allows the direct oxygen alkenylation of dialkyl phosphonates with alkenyl(aryl)iodonium salts with selective transfer of the alkenyl group. This novel methodology proceeds with a wide range of phosphonates under mild conditions and gives straightforward access to valuable enol phosphonates in very good yields. Beilstein J. Org. Chem. 2020, 16, 611–615. doi:10.3762/bjoc.16.56