Metal-free visible-light-enabled vicinal trifluoromethyl dithiolation of unactivated alkenes (Beilstein Journal of Organic Chemistry)

Abstract The difunctionalization of alkenes involving a trifluoromethylthio group (SCF3) for the conversion of versatile and readily available olefins into structurally more complex molecules has been successfully studied. However, the disproportionate dithiolation of alkenes is unknown. Herein, a transition-metal-free protocol is presented for the vicinal trifluoromethylthio–thiolation of unactivated alkenes via a radical process under mild conditions with a broad substrate scope and excellent tolerance. Beilstein J. Org. Chem. 2021, 17, 551–557. doi:10.3762/bjoc.17.49