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RSS FeedsMarine Drugs, Vol. 20, Pages 496: Carotenoids Biosynthesis, Accumulation, and Applications of a Model Microalga Euglena gracilis (Marine Drugs)

 
 

31 july 2022 12:15:14

 
Marine Drugs, Vol. 20, Pages 496: Carotenoids Biosynthesis, Accumulation, and Applications of a Model Microalga Euglena gracilis (Marine Drugs)
 


The carotenoids, including lycopene, lutein, astaxanthin, and zeaxanthin belong to the isoprenoids, whose basic structure is made up of eight isoprene units, resulting in a C40 backbone, though some of them are only trace components in Euglena. They are essential to all photosynthetic organisms due to their superior photoprotective and antioxidant properties. Their dietary functions decrease the risk of breast, cervical, vaginal, and colorectal cancers and cardiovascular and eye diseases. Antioxidant functions of carotenoids are based on mechanisms such as quenching free radicals, mitigating damage from reactive oxidant species, and hindering lipid peroxidation. With the development of carotenoid studies, their distribution, functions, and composition have been identified in microalgae and higher plants. Although bleached or achlorophyllous mutants of Euglena were among the earliest carotenoid-related microalgae under investigation, current knowledge on the composition and biosynthesis of these compounds in Euglena is still elusive. This review aims to overview what is known about carotenoid metabolism in Euglena, focusing on the carotenoid distribution and structure, biosynthesis pathway, and accumulation in Euglena strains and mutants under environmental stresses and different culture conditions. Moreover, we also summarize the potential applications in therapy preventing carcinogenesis, cosmetic industries, food industries, and animal feed.


 
102 viewsCategory: Biochemistry, Molecular Biology, Pharmacology
 
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