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RSS FeedsWee1 promotes cell proliferation and imatinib resistance in chronic myeloid leukemia via regulating DNA damage repair dependent on ATM-γH2AX-MDC1 (Cell Communication and Signaling)

 
 

27 december 2022 21:20:41

 
Wee1 promotes cell proliferation and imatinib resistance in chronic myeloid leukemia via regulating DNA damage repair dependent on ATM-γH2AX-MDC1 (Cell Communication and Signaling)
 


The treatment of chronic myeloid leukemia (CML) is facing the dilemma of tyrosine kinase inhibitors (TKIs) resistance and disease recurrence. The dysfunctional DNA damage repair mechanism plays an essential ro...


 
95 viewsCategory: Cell Biology
 
BMX, a specific HDAC8 inhibitor, with TMZ for advanced CRC therapy: a novel synergic effect to elicit p53-, β-catenin- and MGMT-dependent apoptotic cell death (Cell Communication and Signaling)
Niche formation and function in developing tissue: studies from the Drosophila ovary (Cell Communication and Signaling)
 
 
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