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RSS FeedsGlutarylation of Histone H4 Lysine 91 Regulates Chromatin Dynamics (Molecular Cell)

 
 

21 november 2019 20:00:54

 
Glutarylation of Histone H4 Lysine 91 Regulates Chromatin Dynamics (Molecular Cell)
 


Bao et al. identify H4 Lys91 glutarylation (H4K91glu) as a new histone mark for active gene expression. H4K91glu is `written` and `erased` by KAT2A and Sirt7, respectively. Sirt7-catalyzed removal of H4K91glu is associated with chromatin condensation during mitosis and in response to DNA damage.


 
204 viewsCategory: Molecular Biology, Cell Biology
 
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