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RSS FeedsCryo-EM Structures of Centromeric Tri-nucleosomes Containing a Central CENP-A Nucleosome (Structure)

 
 

7 january 2020 18:03:46

 
Cryo-EM Structures of Centromeric Tri-nucleosomes Containing a Central CENP-A Nucleosome (Structure)
 


The centromere-specific histone H3 variant, CENP-A, is a crucial epigenetic marker for designating centromeres as sites for kinetochore assembly. Takizawa et al. reconstituted tri-nucleosomes mimicking a centromeric nucleosome arrangement containing the CENP-A nucleosome, and determined their structures by single-particle cryo-EM.


 
197 viewsCategory: Biochemistry
 
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