Biochemistry
 |
|
7 january 2020 18:03:46 |
| Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State (Structure) |
|
Tweet Jansma et al. use cryoelectron microscopy to determine the structure and provide a near-complete atomic model of the Tel1ATM kinase dimer, showing how this DNA-damage response sentinel is kept in an ATP-bound but autoinhibited state prior to proper activation by DNA breaks. |
| 158 viewsCategory: Biochemistry |
 Quantitative Structural Interpretation of Protein Crosslinks (Structure)Cryo-EM Structure of Nucleotide-Bound Tel1ATM Unravels the Molecular Basis of Inhibition and Structural Rationale for Disease-Associated Mutations (Structure) 
|
| blog comments powered by Disqus |
MyJournals.org
The latest issues of all your favorite science journals on one page
The latest issues of all your favorite science journals on one page
