Epigenetic Regulator CoREST Controls Social Behavior in Ants (Molecular Cell)

Glastad et al. find that epigenetic regulation is pivotal in mediating programming and reprogramming of worker ant behavior. The conserved neuronal co-repressor CoREST, working with histone deacetylation, is vital in establishing foraging behavior via binding to and repressing genes that degrade JH, a behaviorally mportant hormone promoting foraging.