Radical Prostatectomy or Observation for Clinically Localized Prostate Cancer: Extended Follow-up of the Prostate Cancer Intervention Versus Observation Trial (PIVOT) (European Urology)

Surgery may be associated with small reductions in all-cause mortality compared with observation in men with early prostate cancer. Strategies are needed to communicate these findings, enhance identification of individuals benefitting from early intervention, and reduce ineffective and/or overtreatment harms.